FAQ's - Small Animal Research Irradiation

  • What if I need higher dose levels or faster throughput?
  • Rad Source produces custom irradiation solutions using our scalable technology.

  • What makes the RS 2000 ideal for small animal research?
  • The RS 2000 is designed to allow irradiation of mice in a filtered cage. We understand husbandry is an important part of the process so protecting the mice from the environment, especially with multiple users, is important.

  • How is the RS 2000 installed?
  • The RS 2000 is delivered by crate and then rolled (its mounted on casters) into your facility. The unit simply requires a dedicated 220 VAC, single phase, 40 amp circuit. Its cooling system is completely self-contained. Installation, calibration, dose mapping, and training is completed in less than one day.

  • How reliable is the RS 2000?
  • The RS 2000 consists of a power supply, radiation tube, control module, chassis, and heat exchanger. Rad Source offers 1, 2, and 3 year extended warranty programs.

  • Are there any down line disposal issues with the RS 2000?
  • No, unlike a nuclear isotope, the RS 2000 is an electronic device that is either on or off. When it is off, there is no radiation being emitted.

  • What is the size of the irradiation field?
  • The radiation plane is in a cone shaped irradiation field and can be set at various levels from 12.39 cm (4.88”) to 35.50cm (13.98”).

  • How does the cost of an RS 2000 compare to that of a gamma (cesium or cobalt) unit?
  • When delivery, licensing, related hazardous material shipping, and set-up costs of a radioisotope system are considered, the RS 2000 costs much less than a typical gamma unit.

  • Do I need a lead lined room or secure access for the RS 2000?
  • No, the RS 2000 is completely self-shielded, needs no additional precautions, and is key operated for user security. Background scatter is lower than Federal and State guidelines.

  • Are there any floor loading or environmental concerns when using the RS 2000?
  • No, the RS 2000 is mounted on wheels and weighs less than 1500 lbs.

  • Do I need a Nuclear Site License or an Radiation Safety Officer (RSO) with the RS 2000?
  • No, the RS 2000 is licensed as a cabinet X-ray system and complies with CFR 21.1020.40.

  • How do dose rates compare to a gamma irradiator?
  • The dose rate of a gamma irradiator is not variable for irradiation buts decreases over time. The RS 2000 allows the user to vary dose rate electronically or by varying distance but remains constant unless changed by the user.

  • What is the dose uniformity of the RS 2000 and how does it compare to a gamma irradiator?
  • Each RS 2000 is calibrated at the factory for maximum uniformity and has 95%, or better uniformity, for an area of 7” x 11” (typical rearing cage) at 1 Gy per minute.

  • How is the RS 2000 similar to gamma irradiator?
  • Both use photons as an irradiation source, creating ionizing radiation. The energy of both is energy per unit volume with 1 Gy from Gamma equal to 1 Gy from X-ray.

  • Is the RS 2000 a direct replacement for a gamma irradiator?
  • Yes, X-rays from the RS 2000 produce equivalent dose in cells and small animals. The energy of the photons is lower, therefore the X-rays must be filtered correctly to shape the beam producing equivalent uniformity.

  • Why we don’t offer a 320kV irradiator for lab research?
  • Our RS 2000 was designed and validated for the Biological Research market’s typical applications: small animals, cell, and tissue work. The RS 2000 has been successfully used for over 10 years by acclaimed research laboratories around the globe. The beam profile (proprietary tube and filtering) of the RS 2000 is “Substantially equivalent to Cesium”.

  • What does CDRH stands for?
  • CDRH stands for the FDA’s Center for Devices and Radiological Health (CDRH). Performance Standards for Ionizing Radiation Emitting Products can be found at CDRH 21CFR1020.40

  • How is the RS 2000 similar to gamma irradiator?
  • Both use photons as an irradiation source, creating ionizing radiation. The energy of both is energy per unit volume with 1 Gy from Gamma equal to 1 Gy from x-ray.

  • Is the RS 2000 a direct replacement for a gamma irradiator?
  • Yes, x-rays from the RS 2000 produce equivalent dose in cells and small animals. The energy of the photons is lower however, and the x-ray must have correct filtration shaping beam to produce equivalent uniformity.

    Welcome to RAD Source

    Since 1997 Rad Source Technologies has been the expert in providing renewable, non-isotope, ionizing radiation replacements for self-shielded gamma irradiators. Currently, there are over 300 renowned hospital, university, and pharmaceutical research institutions using Rad Source X-ray technology. To find out more about our equipment, select your application and you will find equipment specifications, literature references, white papers, training videos, discussion forums, as well as other helpful info.

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