Medulloblastoma is a highly invasive cancer of central nervous system diagnosed mainly in children. Matrix metalloproteinase-9 (MMP-9) and urokinase plasminogen activator receptor (uPAR) are over expressed in several cancers and well established for their roles in tumor progression. The present study is aimed to determine the consequences of targeting these molecules on medulloblastoma progression.

“Paragraph title: Cells Lines, Transfections and Radiation … As a radiation source we used RS 2000 Biological Irradiator (Rad Source Technologies, Inc., Boca Raton, FL).”

(PLoS One 2012 Sep 12)