How To Identify Mold In Cannabis Products
Even cannabis products which are lab tested and sold in dispensaries can develop mold. Temperature, light, humidity and air circulation all play a role in the development of mold. It is harmful to ingest moldy cannabis…
Cannabis and Mold: Everything There is to Know
Mold is a group of microorganisms that grow in humid and damp surroundings with poor air ventilation, according to the Center for Disease Control and Prevention (CDC). It reproduces by generating small, light, fungal spores…
What to Look for in a Good Cannabis Microbial Remediator
By Chris Bond Like any consumer product, cannabis should be tested for quality, safety, and purity. Consumers need to be confident in the information provided on the packaging. Testing is the only way to ensure that a product is what it says it is and holds producers accountable in front of the...Successful Suppression of an Aedes aegypti Field Population in Cuba
The sterile insect technique (SIT) is a species-specific and environment-friendly method of insect control that relies on the release of large numbers of sterile insects. Mating released sterile males with wild females leads to a decrease in the reproductive potential and to the local suppression...Looking Skyward to Take on Major Pest of the Nut Industry
ARS is rebooting an old farming technique to fight the navel orangeworm An Agricultural Research Service (ARS) scientist in California is developing a new use for a tool that farmers have had in their kit for over 100 years — aircraft. Heavier-than-air flying machines have aided agriculture since...Revolutionary Quastar ® Technology For Cannabis Decontamination The Focus Of Newly Relaunched Rad Source Life Science Brand
Buford, Georgia (October 12, 2020) — Rad Source Technologies, Inc. (Rad Source), a global life science leader whose proprietary Quastar technology has revolutionized the use of photonic decontamination for a range of sensitive life science end-use applications, has unveiled its new brand identity...Rad Source Technologies Announces Newly Redesigned Rs 3400 Blood Irradiator For 2021
Rad Source Technologies, Inc. (Rad Source), a global leader in developing x-ray solutions for life science is pleased to introduce an update to the industry’s premier blood irradiator, the RS 3400. The newly redesigned FDA-cleared RS 3400, powered by the patented Quastar® x-ray emitter and blood...Revolutionary Quastar ® Technology For Cannabis Decontamination The Focus Of Newly Relaunched Rad Source Life Science Brand
Rad Source Technologies, Inc. (Rad Source), a global life science leader whose proprietary Quastar technology has revolutionized the use of photonic decontamination for a range of sensitive life science end-use applications, has unveiled its new brand identity and revamped website to better...Apoptosis Induced by Knockdown of uPAR and MMP-9 is Mediated by Inactivation of EGFR/STAT3 Signaling in Medulloblastoma
Medulloblastoma is a highly invasive cancer of central nervous system diagnosed mainly in children. Matrix metalloproteinase-9 (MMP-9) and urokinase plasminogen activator receptor (uPAR) are over expressed in several cancers and well established for their roles in tumor progression. The present...Thioridazine Sensitizes Esophageal Carcinoma Cell Lines to Radiotherapy-Induced Apoptosis In Vitro and In Vivo
Combined treatment with thioridazine and irradiation significantly reduced viability of ESCC cells compared with thioridazine or irradiation treatment alone. Thioridazine and irradiation treatment induced G0/G1 phases cell cycle arrest through down-regulation of CDK4 and cyclinD1. In addition,...XactMice: humanizing mouse bone marrow enables microenvironment reconstitution in a patient-derived xenograft model of head and neck cancer
The limitations of cancer cell lines have led to the development of direct patient derived xenograft (PDX) models. However, the interplay between the implanted human cancer cells and recruited mouse stromal and immune cells alters the tumor microenvironment and limits the value of these models. To...What does CDRH stand for?
CDRH stands for the FDA’s Center for Devices and Radiological Health (CDRH). Performance Standards for Ionizing Radiation Emitting Products can be found at CDRH 21CFR1020.40
Short Communication: Nanoparticle Thermotherapy and External Beam Radiation Therapy for Human Prostate Cancer Cells
Abstract: Nanoparticle thermotherapy (NPTT) uses monoclonal antibody-linked iron oxide magnetic nanoparticles (bioprobes) for the tumor-specific thermotherapy of cancer by hysteretic heating of the magnetic component of the probes through an externally applied alternating magnetic field (AMF). The...Endogenous Mouse Dicer Is an Exclusively Cytoplasmic Protein
Dicer is a large multi-domain protein responsible for the ultimate step of microRNA and short-interfering RNA biogenesis. In human and mouse cell lines, Dicer has been shown to be important in the nuclear clearance of dsRNA as well as the establishment of chromatin modifications. Here we set out...Cancer therapies activate RIG-I-like receptor pathway through endogenous non-coding RNAs
Emerging evidence indicates that ionizing radiation (IR) and chemotherapy activate Type I interferon (IFN) signaling in tumor and host cells. However, the mechanism of induction is poorly understood. We identified a novel radioprotective role for the DEXH box RNA helicase LGP2 (DHX58) through its...Cathepsin B and uPAR regulate self-renewal of glioma-initiating cells through GLI-regulated Sox2 and Bmi1 expression
Cancer-initiating cells comprise a heterogeneous population of undifferentiated cells with the capacity for self-renewal and high proliferative potential. We investigated the role of uPAR and cathepsin B in the maintenance of stem cell nature in glioma-initiating cells (GICs). Simultaneous...Thiol/Redox Metabolomic Profiling Implicates GSH Dysregulation in Early Experimental Graft versus Host Disease (GVHD)
Graft-versus-host disease (GVHD) is a common complication of allogeneic bone marrow transplantation (BMT). Upregulation of inflammatory cytokines precedes the clinical presentation of GVHD and predicts its severity. In this report, thiol/redox metabolomics was used to identify metabolic...Using Nanodot Dosimetry to Study the RS 2000 X-Ray Biological Irradiator
AbstractPurpose: To use NanoDot dosimeters to study the RS 2000 X-ray Biological Irradiator dosimetry characteristics and perform in vivo dosimetry for cell or small animal experiments. Methods and materials: We first calibrated the Landauer NanoDot™ Reader by irradiating some NanoDot dosimeters...Rac2-MRC-cIII–generated ROS cause genomic instability in chronic myeloid leukemia stem cells and primitive progenitors
Chronic myeloid leukemia in chronic phase (CML-CP) is induced by BCR-ABL1 oncogenic tyrosine kinase. Tyrosine kinase inhibitors eliminate the bulk of CML-CP cells, but fail to eradicate leukemia stem cells (LSCs) and leukemia progenitor cells (LPCs) displaying innate and acquired resistance,...Control of Listeria Monocytogenes and Spoilage Bacteria on Smoked Salmon During Storage At 5 °C Aft
Full Title – Control of Listeria monocytogenes and spoilage bacteria on smoked salmon during storage at 5 °C after X-ray irradiation Abstract In this study, smoked salmon fillets were artificially inoculated with Listeriamonocytogenes (3.7 ± 0.2 log CFU g−1) and treated with X-ray...Suppression of uPA and uPAR Blocks Radiation-induced MCP-1 mediated Recruitment of Endothelial Cells and Monocytes in meningioma
Chemokines play a vital role in recruiting various cell types in the process of tissue repair. Radiation, a major therapeutic modality in cancer treatment, has been described to induce inflammatory response that might lead to the expression of several chemokines. In the present study, we...Poly(ADP-ribose) polymerase inhibition synergizes with 5-fluorodeoxyuridine but not 5-fluorouracil in ovarian cancer cells
5-Fluorouracil (5-FU) and 5-fluorodeoxyuridine (FdUrd, floxuridine) have activity in multiple tumors, and both agents undergo intracellular processing to active metabolites that disrupt RNA and DNA metabolism. These agents cause imbalances in dNTP levels and the accumulation of uracil and 5-FU in...The Application of Radiation Therapy to the Pediatric Preclinical Testing Program
Abstract:BACKGROUND:The Pediatric Preclinical Testing Program (PPTP) has been successfully used to determine the efficacy of novel agents against solid tumors by testing them within a mouse-flank in vivo model. To date, radiation therapy has not been applied to this system. We report on the...Effects Of X-Ray Treatments On Bacteria, Microflora, Color, And Firmness On Whole Cantaloupe
Full Title – Effects of X-ray treatments on pathogenic bacteria, inherent microflora, color, and firmness on whole cantaloupe. Mahmoud BS. Source Coastal Research & Extension Center, Mississippi State University, Pascagoula, MS 39567, United States. bm547@msstate.edu Abstract...Reduction In Listeria Monocytogenes And Spoilage Bacteria On Smoked Catfish Using X-Ray Treatments
To determine the efficacy of X-ray processes in inactivating L. monocytogenes levels in smoked catfish during storage at 5°C and to determine the effects of X-ray doses on controlling the growth of spoilage bacteria on smoked catfish during storage at 5°C for up to 5 weeks.