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RS 3400
Blood Irradiation
The world’s premier blood irradiator just raised the bar on dose uniformity, productivity, and throughput.
See The RS 3400 In Action
Superior Throughput, Dose Uniformity & Simplicity of Ownership
We pioneered the first-ever FDA-approved blood x-ray irradiation medical device used to prevent the transfusion-associated graft-versus-host disease (TA-GVHD) in blood transfusion recipients.
Available Components & Accessories
Contact Our Experts
RS 3400 One World Design Product Brochure
International
RS 3400 One World Design Product Brochure
Domestic United States
Features and Specifications
Unmatched Dose Uniformity
Dose Uniformity of 1.6 to ~ 1.36
Industry Leading Cycle Time
Cycle time for 25Gy center dose is less than 5 minutes.
Patented Carousel Rotator
- Uniquely rotates canisters around source w/out rotating contents.
- Holds up to (6) 1 L canisters.
- Can process blood bags, platelet bags, and drawn syringes of up to 60 mL (e.g. aliquots) in the cycle.
Direct Cesium Replacement
- No Nuclear Regulatory Commission (NRC) License required.
- No nuclear disposal requirements.
- No additional safety equipment for laboratory staff.
- No additional security requirements.
Simple Power Requirements
- Runs on a single power supply.
- Runs at less than 2 kW.
Repairable X-Ray Emitter
Emitter source is repairable and can operate up to 7 years or more.
Smallest blood irradiator footprint
33.3 x 33.9″ | 84.6 x 86.0 cm
Certifications
US-FDA cleared, CE marked, and CB Scheme certified.
Onboard Cooling System
No facilities water hook-up or plumbing required.
PHYSICAL DIMENSIONS (W x D x H)
33.9 x 33.35 x 68.25 ” | 86 x 84.6 x 173.35 cm
EQUIPMENT WEIGHT
1735 lbs. | 786.98 kg
ELECTRICAL REQUIREMENTS
Power: 208/240VAC, Single phase, 50/60Hz, 30 Amp, true earth ground. Instrument Wiring: 10 AWG L1, L2/N.
USA (FDA)
25 Gy min/ 50 Gy max dose rate: 5.5 – 6.5 Gy/min
EUROPE (EDQM) & UK (BCSH)
25 Gy min./ 50 Gy max dose rate: 25 Gy/min. Dose rate: 5.5-6.5 Gy/min.
DOSE UNIFORMITY RATIO (DUR)
~1.6 to as low as ~1.35* (*when using the Support Inserts)
PROCESSING VOLUME / CYCLE
Blood Bags – Up to (6) 600 mL bags, Platelet Bags – Up to (6) 500 mL bag, Syringes – Up to (18) 60 mL Syringes
DOSE MAPPING
The RS 3400 is dose mapped prior to shipment and at the time of installation. Semi-Annual Dose Maps are provided by Rad Source during the Warranty and Extended Warranty periods.
12 MONTH FULL WARRANTY
Includes Installation, Training, Initial Dose Map, Radiation Survey, 2nd Dose Map, and all parts, labor & travel.
EXTENDED WARRANTY PROGRAM
Available for purchase anytime within 12 months from the date of installation. Contact for details.
INTERNATIONAL WARRANTIES
Contact Your Distributor for details.
- All Rad Source irradiators receive a quality inspection, dose map, and radiation survey prior to shipment and again at installation.
- All Rad Source irradiators are manufactured as cabinet x-ray devices and conform to the radiation safety guidelines in 21 CFR 1020.40
- All Rad Source irradiators are manufactured as cabinet x-ray devices and conform to the radiation safety guidelines in complies with Canadian REDA requirements
FAQs
Does the RS 3400 Require External Cooling?
No, the RS 3400 uses a self-contained water-to-air exchange system.
How does the RS 3400 Blood Irradiator differ from other x-ray irradiators?
- The RS 3400 has a 6 Liter capacity allowing multiple products in the same cycle whether it be whole blood, platelets, or loaded syringes. Rad Source is the only company with an x-ray emitter that was designed specifically for biological irradiation.
- The RS 3400 is designed to rotate blood bags around the Quastar™ x-ray emitter using our patented carousel and, therefore, delivers superior uniformity.
- Unlike other x-ray blood irradiators, the RS 3400 is entirely self-contained and requires no external water supply for tube cooling.
- The RS 3400 is engineered for extreme reliability as it uses the proven Quastar™ x-ray emitter.
- The RS 3400 has only ONE x-ray tube and ONE power supply.
How Does the RS 3400 Differ From a CS-137 Gamma Irradiator?
- The RS 3400 Blood Irradiator uses a Rad Source patented Quastar™ x-ray emitter and therefore contains NO radioactive isotopes.
- It can be turned on and off, similar to a light bulb.
- As a result, there are no Nuclear Site License, Homeland Security issues, or room shielding requirements.
How is Ionizing Radiation Generated?
- Ionizing radiation comes from radioactive sources such as cobalt 60 and cesium 137 and non-radioactive sources such as x-ray tubes.
- Radioactive sources are unstable materials where gamma rays originate from the nucleus.
- X-rays originate in the electron fields surrounding the nucleus or are machine-produced.
What Is Ionizing Radiation?
- Ionizing radiation consists of subatomic particles or electromagnetic waves that are energetic enough to detach electrons from atoms or molecules, ionizing them.
- Two of the most common forms of ionizing radiation are gamma rays and x-rays. Both forms of ionizing radiation are almost identical except for their source of origination.
Why is Ionizing Radiation Used?
Because of the penetrating properties of ionizing radiation and their ability to inactivate microorganisms, ionizing radiation is used to sterilize or reduce the microbial load of many different types of products such as medical devices, packaging, cosmetics, foods, and agricultural products. It is also used to alter the properties of many different polymers through recombination, cross-linkage, and cross scission.
Why Use X-ray Versus Gamma-Produced Ionizing Radiation?
- Gamma ionizing radiation is produced by radioactive sources such as cobalt 60 or cesium 137 and is dangerous, requiring heavy shielding and high levels of security to protect.
- The unstable material is constantly decaying and cannot be turned off. X-ray ionizing radiation is produced by an x-ray tube; therefore, it can be turned off when not in use, requiring much less shielding. At the end of the unit’s lifecycle, the unit does not have any radioactive source.
- It does not require the expensive disposal costs associated with radioactive sources that continue to degrade over hundreds of years.
Latest News & Studies
Thiol/Redox Metabolomic Profiling Implicates GSH Dysregulation in Early Experimental Graft versus Host Disease (GVHD)
Graft-versus-host disease (GVHD) is a common complication of allogeneic bone marrow transplantation (BMT). Upregulation of inflammatory cytokines precedes the clinical presentation of GVHD and predicts its severity. In this...
Characterization and Dosimetry of a Practical X-Ray Alternative to Self-Shielded Gamma Irradiators
Kishor Mehta, Andrew Parker Insect Pest Control Laboratory, Joint FAO/IAEA Division of Nuclear Techniques in Food and Agriculture, International Atomic Energy Agency, Vienna, Austria Received 19 February 2010; Accepted 22 August...
Sealed Source Disposal And National Security – Problem Statement And Solution Set
While gamma rays have been a reliable source, the isotopes, primarily cobalt-60 and cesium-137, used to generate these gamma rays have come under heavy scrutiny worldwide in recent years. To quote the abstract of a recent...